diff --git a/GPU/Common/TextureReplacer.cpp b/GPU/Common/TextureReplacer.cpp
index 90a9f8b8ab..b143de8e11 100644
--- a/GPU/Common/TextureReplacer.cpp
+++ b/GPU/Common/TextureReplacer.cpp
@@ -367,6 +367,9 @@ bool TextureReplacer::LoadIniValues(IniFile &ini, VFSBackend *dir, bool isOverri
 	}
 	options->Get("skipLastDXT1Blocks128x64", &skipLastDXT1Blocks128x64_);
 	options->Get("skipLastDXT1Blocks128x128", &skipLastDXT1Blocks128x128_);
+	// These are subtracted from the hashed size, so can't be more than the blocks there are.
+	skipLastDXT1Blocks128x64_ = std::clamp(skipLastDXT1Blocks128x64_, 0, (128 / 4) * (64 / 4));
+	skipLastDXT1Blocks128x128_ = std::clamp(skipLastDXT1Blocks128x128_, 0, (128 / 4) * (128 / 4));
 	if (reduceHash_ && textureHash_ == ReplacedTextureHash::QUICK) {
 		reduceHash_ = false;
 		ERROR_LOG(Log::TexReplacement, "Texture Replacement: reduceHash option requires safer hash, use xxh32 or xxh64 instead.");
@@ -635,11 +638,12 @@ u32 TextureReplacer::ComputeHash(u32 addr, int bufw, int w, int h, bool swizzled
 		}
 
 		// Hack for Yu Gi Oh texture hashing problem. See issue #19714
-		if (skipLastDXT1Blocks128x64_ && fmt == GE_TFMT_DXT1 && w == 128 && h == 64) {
+		// (reduceHash can make sizeInRAM smaller than all the blocks, so check it can't underflow.)
+		if (skipLastDXT1Blocks128x64_ && fmt == GE_TFMT_DXT1 && w == 128 && h == 64 && (u32)(8 * skipLastDXT1Blocks128x64_) < (u32)sizeInRAM) {
 			// Skip the last few blocks as specified.
 			sizeInRAM -= 8 * skipLastDXT1Blocks128x64_;
 		}
-		if (skipLastDXT1Blocks128x128_ && fmt == GE_TFMT_DXT1 && w == 128 && h == 128) {
+		if (skipLastDXT1Blocks128x128_ && fmt == GE_TFMT_DXT1 && w == 128 && h == 128 && (u32)(8 * skipLastDXT1Blocks128x128_) < (u32)sizeInRAM) {
 			sizeInRAM -= 8 * skipLastDXT1Blocks128x128_;
 		}
 
diff --git a/UI/BackgroundAudio.cpp b/UI/BackgroundAudio.cpp
index 36f8322b64..ffc475cd5c 100644
--- a/UI/BackgroundAudio.cpp
+++ b/UI/BackgroundAudio.cpp
@@ -2,6 +2,7 @@
 #include <string>
 #include <mutex>
 #include <algorithm>
+#include <climits>
 
 #include "Common/File/VFS/VFS.h"
 #include "Common/UI/Root.h"
@@ -132,14 +133,19 @@ bool WavData::Read(RIFFReader &file_) {
 					int samplesPerFrame = codec == PSP_CODEC_AT3PLUS ? 2048 : 1024;
 
 					for (int i = 0; i < numLoops; ++i) {
-						// Only seen forward loops, so let's ignore others.
-						if (loops[i].type != 0)
+						// Only seen forward loops, so let's ignore others. Also ones that don't go forwards,
+						// which would point playback before the data.
+						if (loops[i].type != 0 || loops[i].startSample < 0 || loops[i].endSample <= loops[i].startSample)
 							continue;
 
 						// We ignore loop interpolation (fraction) and play count for now.
-						raw_offset_loop_start = (loops[i].startSample / samplesPerFrame) * raw_bytes_per_frame;
+						const s64 loopStart = (s64)(loops[i].startSample / samplesPerFrame) * raw_bytes_per_frame;
+						const s64 loopEnd = (s64)(loops[i].endSample / samplesPerFrame) * raw_bytes_per_frame;
+						if (loopEnd > INT_MAX)
+							continue;
+						raw_offset_loop_start = (int)loopStart;
 						loop_start_offset = loops[i].startSample % samplesPerFrame;
-						raw_offset_loop_end = (loops[i].endSample / samplesPerFrame) * raw_bytes_per_frame;
+						raw_offset_loop_end = (int)loopEnd;
 						loop_end_offset = loops[i].endSample % samplesPerFrame;
 
 						if (loops[i].playCount == 0) {
@@ -201,6 +207,14 @@ bool WavData::Read(RIFFReader &file_) {
 		ERROR_LOG(Log::Audio, "Could not descend into RIFF file.");
 		return false;
 	}
+	// The loop points came from the smpl chunk, so they have to land in the data. The sample
+	// offsets (within a frame) are always positive, since the loop samples were checked above.
+	if (raw_offset_loop_start < 0 || raw_offset_loop_end > raw_data_size || raw_offset_loop_start > raw_offset_loop_end) {
+		raw_offset_loop_start = 0;
+		raw_offset_loop_end = 0;
+		loop_start_offset = 0;
+		loop_end_offset = 0;
+	}
 	sample_rate = samplesPerSec;
 	return true;
 }
diff --git a/UI/ImposeHome.cpp b/UI/ImposeHome.cpp
index b4f8fa1af5..dfc99e7160 100644
--- a/UI/ImposeHome.cpp
+++ b/UI/ImposeHome.cpp
@@ -298,7 +298,7 @@ bool ImposeArt::Parse(const std::vector<uint8_t> &file, int pspLanguage) {
 		const uint32_t w = r.U32(rec + 16);
 		const uint32_t h = r.U32(rec + 20);
 		const uint32_t offset = r.U32(rec + 24);
-		if (!r.ok || palette >= NUM_PALETTES || w == 0 || h == 0 || x + w > PSP_W || y + h > PSP_H || (w * h + 1) / 2 != size) {
+		if (!r.ok || palette >= NUM_PALETTES || w == 0 || h == 0 || w > PSP_W || x > PSP_W - w || h > PSP_H || y > PSP_H - h || (w * h + 1) / 2 != size) {
 			return false;
 		}
 		const size_t pixels = block + TEXT_RECORDS + (size_t)offset;
diff --git a/UI/Store.cpp b/UI/Store.cpp
index 1e8e67529d..65cbb8c8a2 100644
--- a/UI/Store.cpp
+++ b/UI/Store.cpp
@@ -448,7 +448,9 @@ void StoreScreen::ParseListing(const std::string &json) {
 			// (Path::operator/ does no ".." normalization); on platforms/builds where
 			// the store index isn't fetched over HTTPS, a MITM'd or compromised
 			// response could otherwise point "launch" at an arbitrary host path.
-			if (HasParentDirComponent(file))
+			// It's also uninstalled (deleted recursively) by name, so "." or "/" would be the
+			// whole GAME directory.
+			if (HasParentDirComponent(file) || !IsSafePathComponent(file))
 				continue;
 			e.file = file;
 			entries_.push_back(e);
diff --git a/headless/Compare.cpp b/headless/Compare.cpp
index 16e7897dad..e35e9a667d 100644
--- a/headless/Compare.cpp
+++ b/headless/Compare.cpp
@@ -403,6 +403,13 @@ double ScreenshotComparer::Compare(const Path &screenshotFilename) {
 				return -1.0f;
 			}
 
+			// Everything below reads w_ x h_ pixels from it.
+			if (width < (int)w_ || height < (int)h_) {
+				error_ = StringFromFormat("Screenshot is too small (%dx%d, expected %dx%d): %s", width, height, (int)w_, (int)h_, screenshotFilename.ToVisualString().c_str());
+				free(reference_);
+				reference_ = nullptr;
+				return -1.0f;
+			}
 			referenceStride_ = width;
 		}
 	} else {