diff --git a/Common/GPU/Vulkan/VulkanDebug.cpp b/Common/GPU/Vulkan/VulkanDebug.cpp
index f165d73609..acfd81b1d5 100644
--- a/Common/GPU/Vulkan/VulkanDebug.cpp
+++ b/Common/GPU/Vulkan/VulkanDebug.cpp
@@ -37,6 +37,11 @@ VKAPI_ATTR VkBool32 VKAPI_CALL VulkanDebugUtilsCallback(
 		// UNASSIGNED-CoreValidation-Shader-OutputNotConsumed - benign perf warning
 		return false;
 	}
+	if (messageCode == 1303270965) {
+		// Benign perf warning, image blit using GENERAL layout.
+		// UNASSIGNED
+		return false;
+	}
 
 	const char *pLayerPrefix = "";
 	if (messageSeverity & VK_DEBUG_UTILS_MESSAGE_SEVERITY_ERROR_BIT_EXT) {
diff --git a/Common/GPU/Vulkan/VulkanImage.cpp b/Common/GPU/Vulkan/VulkanImage.cpp
index 5301a47803..c6b99f28d9 100644
--- a/Common/GPU/Vulkan/VulkanImage.cpp
+++ b/Common/GPU/Vulkan/VulkanImage.cpp
@@ -196,7 +196,8 @@ void VulkanTexture::ClearMip(VkCommandBuffer cmd, int mip, uint32_t value) {
 	vkCmdClearColorImage(cmd, image_, VK_IMAGE_LAYOUT_TRANSFER_DST_OPTIMAL, &clearVal, 1, &range);
 }
 
-void VulkanTexture::GenerateMip(VkCommandBuffer cmd, int mip) {
+// Low-quality mipmap generation by bilinear blit, but works okay.
+void VulkanTexture::GenerateMip(VkCommandBuffer cmd, int mip, VkImageLayout imageLayout) {
 	_assert_msg_(mip != 0, "Cannot generate the first level");
 	_assert_msg_(mip < numMips_, "Cannot generate mipmaps past the maximum created (%d vs %d)", mip, numMips_);
 	VkImageBlit blit{};
@@ -214,16 +215,20 @@ void VulkanTexture::GenerateMip(VkCommandBuffer cmd, int mip) {
 	blit.dstOffsets[1].y = height_ >> mip;
 	blit.dstOffsets[1].z = 1;
 
+	// TODO: We could do better with the image transitions - would be enough with one per level
+	// for the memory barrier, then one final one for the whole stack when done. This function
+	// currently doesn't have a global enough view, though.
+	// We should also coalesce barriers across multiple texture uploads in a frame and all kinds of other stuff, but...
+
 	TransitionImageLayout2(cmd, image_, mip - 1, 1, VK_IMAGE_ASPECT_COLOR_BIT,
-		VK_IMAGE_LAYOUT_TRANSFER_DST_OPTIMAL, VK_IMAGE_LAYOUT_TRANSFER_SRC_OPTIMAL,
+		imageLayout, VK_IMAGE_LAYOUT_TRANSFER_SRC_OPTIMAL,
 		VK_PIPELINE_STAGE_TRANSFER_BIT, VK_PIPELINE_STAGE_TRANSFER_BIT,
 		VK_ACCESS_TRANSFER_WRITE_BIT, VK_ACCESS_TRANSFER_READ_BIT);
 
-	// Low-quality mipmap generation, but works okay.
-	vkCmdBlitImage(cmd, image_, VK_IMAGE_LAYOUT_TRANSFER_SRC_OPTIMAL, image_, VK_IMAGE_LAYOUT_TRANSFER_DST_OPTIMAL, 1, &blit, VK_FILTER_LINEAR);
+	vkCmdBlitImage(cmd, image_, VK_IMAGE_LAYOUT_TRANSFER_SRC_OPTIMAL, image_, imageLayout, 1, &blit, VK_FILTER_LINEAR);
 
 	TransitionImageLayout2(cmd, image_, mip - 1, 1, VK_IMAGE_ASPECT_COLOR_BIT,
-		VK_IMAGE_LAYOUT_TRANSFER_SRC_OPTIMAL, VK_IMAGE_LAYOUT_TRANSFER_DST_OPTIMAL,
+		VK_IMAGE_LAYOUT_TRANSFER_SRC_OPTIMAL, imageLayout,
 		VK_PIPELINE_STAGE_TRANSFER_BIT, VK_PIPELINE_STAGE_TRANSFER_BIT,
 		VK_ACCESS_TRANSFER_READ_BIT, VK_ACCESS_TRANSFER_WRITE_BIT);
 }
diff --git a/Common/GPU/Vulkan/VulkanImage.h b/Common/GPU/Vulkan/VulkanImage.h
index 0745e0e352..be0367aee0 100644
--- a/Common/GPU/Vulkan/VulkanImage.h
+++ b/Common/GPU/Vulkan/VulkanImage.h
@@ -21,7 +21,7 @@ public:
 	bool CreateDirect(VkCommandBuffer cmd, VulkanDeviceAllocator *allocator, int w, int h, int numMips, VkFormat format, VkImageLayout initialLayout, VkImageUsageFlags usage = VK_IMAGE_USAGE_TRANSFER_DST_BIT | VK_IMAGE_USAGE_SAMPLED_BIT, const VkComponentMapping *mapping = nullptr);
 	void ClearMip(VkCommandBuffer cmd, int mip, uint32_t value);
 	void UploadMip(VkCommandBuffer cmd, int mip, int mipWidth, int mipHeight, VkBuffer buffer, uint32_t offset, size_t rowLength);  // rowLength is in pixels
-	void GenerateMip(VkCommandBuffer cmd, int mip);
+	void GenerateMip(VkCommandBuffer cmd, int mip, VkImageLayout imageLayout);
 	void EndCreate(VkCommandBuffer cmd, bool vertexTexture = false, VkImageLayout layout = VK_IMAGE_LAYOUT_TRANSFER_DST_OPTIMAL);
 
 	// When loading mips from compute shaders, you need to pass VK_IMAGE_LAYOUT_GENERAL to the above function.
diff --git a/Common/GPU/Vulkan/thin3d_vulkan.cpp b/Common/GPU/Vulkan/thin3d_vulkan.cpp
index 36f480a645..e0ffa8f644 100644
--- a/Common/GPU/Vulkan/thin3d_vulkan.cpp
+++ b/Common/GPU/Vulkan/thin3d_vulkan.cpp
@@ -755,7 +755,7 @@ bool VKTexture::Create(VkCommandBuffer cmd, VulkanPushBuffer *push, const Textur
 		}
 		// Generate the rest of the mips automatically.
 		for (; i < mipLevels_; i++) {
-			vkTex_->GenerateMip(cmd, i);
+			vkTex_->GenerateMip(cmd, i, VK_IMAGE_LAYOUT_TRANSFER_DST_OPTIMAL);
 		}
 	}
 	vkTex_->EndCreate(cmd, false);
diff --git a/GPU/Vulkan/TextureCacheVulkan.cpp b/GPU/Vulkan/TextureCacheVulkan.cpp
index e568869b10..e0977a4512 100644
--- a/GPU/Vulkan/TextureCacheVulkan.cpp
+++ b/GPU/Vulkan/TextureCacheVulkan.cpp
@@ -930,6 +930,7 @@ void TextureCacheVulkan::BuildTexture(TexCacheEntry *const entry) {
 			void *data;
 			bool dataScaled = true;
 			if (replaced.Valid()) {
+				// Directly load the replaced image.
 				data = drawEngine_->GetPushBufferForTextureData()->PushAligned(size, &bufferOffset, &texBuf, pushAlignment);
 				replaced.Load(i, data, stride);
 				entry->vkTex->UploadMip(cmdInit, i, mipWidth, mipHeight, texBuf, bufferOffset, stride / bpp);
@@ -1010,7 +1011,7 @@ void TextureCacheVulkan::BuildTexture(TexCacheEntry *const entry) {
 
 		// Generate any additional mipmap levels.
 		for (int level = maxLevel + 1; level <= maxLevelToGenerate; level++) {
-			entry->vkTex->GenerateMip(cmdInit, level);
+			entry->vkTex->GenerateMip(cmdInit, level, computeUpload ? VK_IMAGE_LAYOUT_GENERAL : VK_IMAGE_LAYOUT_TRANSFER_DST_OPTIMAL);
 		}
 
 		if (maxLevel == 0) {