diff --git a/GPU/GLES/TransformPipeline.cpp b/GPU/GLES/TransformPipeline.cpp
index 86a4dcc0c5..afb2aa39ff 100644
--- a/GPU/GLES/TransformPipeline.cpp
+++ b/GPU/GLES/TransformPipeline.cpp
@@ -539,6 +539,10 @@ void TransformDrawEngine::DoFlush() {
 		if (g_Config.bSoftwareSkinning && (lastVType_ & GE_VTYPE_WEIGHT_MASK))
 			useCache = false;
 
+		// Also avoid caching when HW T&L with morph enabled.
+		if (g_Config.bHardwareTransform && !(lastVType_ & GE_VTYPE_MORPHCOUNT_MASK))
+			useCache = false;
+
 		if (useCache) {
 			u32 id = ComputeFastDCID();
 			auto iter = vai_.find(id);