diff --git a/Core/Config.cpp b/Core/Config.cpp
index bf95896234..5241f8c2aa 100644
--- a/Core/Config.cpp
+++ b/Core/Config.cpp
@@ -959,6 +959,8 @@ static ConfigSetting controlSettings[] = {
 	ConfigSetting("MouseSensitivity", &g_Config.fMouseSensitivity, 0.1f, true, true),
 	ConfigSetting("MouseSmoothing", &g_Config.fMouseSmoothing, 0.9f, true, true),
 
+	ConfigSetting("SystemControls", &g_Config.bSystemControls, true, true, false),
+
 	ConfigSetting(false),
 };
 
diff --git a/Core/Config.h b/Core/Config.h
index 8eeeea1e10..0c1221cca0 100644
--- a/Core/Config.h
+++ b/Core/Config.h
@@ -398,6 +398,8 @@ public:
 	float fMouseSensitivity;
 	float fMouseSmoothing;
 
+	bool bSystemControls;
+
 	// Use the hardware scaler to scale up the image to save fillrate. Similar to Windows' window size, really.
 	int iAndroidHwScale;  // 0 = device resolution. 1 = 480x272 (extended to correct aspect), 2 = 960x544 etc.
 
diff --git a/UI/GameSettingsScreen.cpp b/UI/GameSettingsScreen.cpp
index 526eafd389..990ba1c8e1 100644
--- a/UI/GameSettingsScreen.cpp
+++ b/UI/GameSettingsScreen.cpp
@@ -649,6 +649,7 @@ void GameSettingsScreen::CreateViews() {
 	controlsSettings->Add(new Choice(co->T("Control Mapping")))->OnClick.Handle(this, &GameSettingsScreen::OnControlMapping);
 
 #if defined(USING_WIN_UI)
+	controlsSettings->Add(new CheckBox(&g_Config.bSystemControls, co->T("Enable standard shortcut keys")));
 	controlsSettings->Add(new CheckBox(&g_Config.bGamepadOnlyFocused, co->T("Ignore gamepads when not focused")));
 #endif
 
diff --git a/Windows/MainWindowMenu.cpp b/Windows/MainWindowMenu.cpp
index 567635ffe5..b5dad2a693 100644
--- a/Windows/MainWindowMenu.cpp
+++ b/Windows/MainWindowMenu.cpp
@@ -244,9 +244,9 @@ namespace MainWindow {
 
 		// Emulation menu
 		TranslateMenuItem(menu, ID_EMULATION_PAUSE);
-		TranslateMenuItem(menu, ID_EMULATION_STOP, L"\tCtrl+W");
-		TranslateMenuItem(menu, ID_EMULATION_RESET, L"\tCtrl+B");
-		TranslateMenuItem(menu, ID_EMULATION_SWITCH_UMD, L"\tCtrl+U");
+		TranslateMenuItem(menu, ID_EMULATION_STOP, g_Config.bSystemControls ? L"\tCtrl+W" : L"");
+		TranslateMenuItem(menu, ID_EMULATION_RESET, g_Config.bSystemControls ? L"\tCtrl+B" : L"");
+		TranslateMenuItem(menu, ID_EMULATION_SWITCH_UMD, g_Config.bSystemControls ? L"\tCtrl+U" : L"");
 		TranslateMenuItem(menu, ID_EMULATION_ROTATION_MENU);
 		TranslateMenuItem(menu, ID_EMULATION_ROTATION_H);
 		TranslateMenuItem(menu, ID_EMULATION_ROTATION_V);
@@ -254,7 +254,7 @@ namespace MainWindow {
 		TranslateMenuItem(menu, ID_EMULATION_ROTATION_V_R);
 
 		// Debug menu
-		TranslateMenuItem(menu, ID_TOGGLE_BREAK, L"\tF8", "Break");
+		TranslateMenuItem(menu, ID_TOGGLE_BREAK, g_Config.bSystemControls ? L"\tF8" : L"", "Break");
 		TranslateMenuItem(menu, ID_DEBUG_BREAKONLOAD);
 		TranslateMenuItem(menu, ID_DEBUG_IGNOREILLEGALREADS);
 		TranslateMenuItem(menu, ID_DEBUG_LOADMAPFILE);
@@ -262,14 +262,14 @@ namespace MainWindow {
 		TranslateMenuItem(menu, ID_DEBUG_LOADSYMFILE);
 		TranslateMenuItem(menu, ID_DEBUG_SAVESYMFILE);
 		TranslateMenuItem(menu, ID_DEBUG_RESETSYMBOLTABLE);
-		TranslateMenuItem(menu, ID_DEBUG_TAKESCREENSHOT, L"\tF12");
+		TranslateMenuItem(menu, ID_DEBUG_TAKESCREENSHOT, g_Config.bSystemControls ? L"\tF12" : L"");
 		TranslateMenuItem(menu, ID_DEBUG_DUMPNEXTFRAME);
 		TranslateMenuItem(menu, ID_DEBUG_SHOWDEBUGSTATISTICS);
-		TranslateMenuItem(menu, ID_DEBUG_DISASSEMBLY, L"\tCtrl+D");
-		TranslateMenuItem(menu, ID_DEBUG_GEDEBUGGER, L"\tCtrl+G");
+		TranslateMenuItem(menu, ID_DEBUG_DISASSEMBLY, g_Config.bSystemControls ? L"\tCtrl+D" : L"");
+		TranslateMenuItem(menu, ID_DEBUG_GEDEBUGGER, g_Config.bSystemControls ? L"\tCtrl+G" : L"");
 		TranslateMenuItem(menu, ID_DEBUG_EXTRACTFILE);
-		TranslateMenuItem(menu, ID_DEBUG_LOG, L"\tCtrl+L");
-		TranslateMenuItem(menu, ID_DEBUG_MEMORYVIEW, L"\tCtrl+M");
+		TranslateMenuItem(menu, ID_DEBUG_LOG, g_Config.bSystemControls ? L"\tCtrl+L" : L"");
+		TranslateMenuItem(menu, ID_DEBUG_MEMORYVIEW, g_Config.bSystemControls ? L"\tCtrl+M" : L"");
 
 		// Options menu
 		TranslateMenuItem(menu, ID_OPTIONS_LANGUAGE);
@@ -287,10 +287,10 @@ namespace MainWindow {
 		TranslateMenuItem(menu, ID_FILE_DUMPAUDIO);
 
 		// Skip display multipliers x1-x10
-		TranslateMenuItem(menu, ID_OPTIONS_FULLSCREEN, L"\tAlt+Return, F11");
+		TranslateMenuItem(menu, ID_OPTIONS_FULLSCREEN, g_Config.bSystemControls ? L"\tAlt+Return, F11" : L"");
 		TranslateMenuItem(menu, ID_OPTIONS_VSYNC);
 		TranslateMenuItem(menu, ID_OPTIONS_SHADER_MENU);
-		TranslateMenuItem(menu, ID_OPTIONS_SCREEN_MENU, L"\tCtrl+1");
+		TranslateMenuItem(menu, ID_OPTIONS_SCREEN_MENU, g_Config.bSystemControls ? L"\tCtrl+1" : L"");
 		TranslateMenuItem(menu, ID_OPTIONS_SCREENAUTO);
 		// Skip rendering resolution 2x-5x..
 		TranslateMenuItem(menu, ID_OPTIONS_WINDOW_MENU);
@@ -304,7 +304,7 @@ namespace MainWindow {
 		TranslateMenuItem(menu, ID_OPTIONS_RENDERMODE_MENU);
 		TranslateMenuItem(menu, ID_OPTIONS_NONBUFFEREDRENDERING);
 		TranslateMenuItem(menu, ID_OPTIONS_BUFFEREDRENDERING);
-		TranslateMenuItem(menu, ID_OPTIONS_FRAMESKIP_MENU, L"\tF7");
+		TranslateMenuItem(menu, ID_OPTIONS_FRAMESKIP_MENU, g_Config.bSystemControls ? L"\tF7" : L"");
 		TranslateMenuItem(menu, ID_OPTIONS_FRAMESKIP_AUTO);
 		TranslateMenuItem(menu, ID_OPTIONS_FRAMESKIP_0);
 		TranslateMenuItem(menu, ID_OPTIONS_FRAMESKIPTYPE_MENU);
@@ -330,8 +330,8 @@ namespace MainWindow {
 		TranslateMenuItem(menu, ID_OPTIONS_VERTEXCACHE);
 		TranslateMenuItem(menu, ID_OPTIONS_SHOWFPS);
 		TranslateMenuItem(menu, ID_EMULATION_SOUND);
-		TranslateMenuItem(menu, ID_EMULATION_CHEATS, L"\tCtrl+T");
-		TranslateMenuItem(menu, ID_EMULATION_CHAT, L"\tCtrl+C");
+		TranslateMenuItem(menu, ID_EMULATION_CHEATS, g_Config.bSystemControls ? L"\tCtrl+T" : L"");
+		TranslateMenuItem(menu, ID_EMULATION_CHAT, g_Config.bSystemControls ? L"\tCtrl+C" : L"");
 
 		// Help menu: it's translated in CreateHelpMenu.
 		CreateHelpMenu(menu);
diff --git a/Windows/main.cpp b/Windows/main.cpp
index c322b755b7..484c487efb 100644
--- a/Windows/main.cpp
+++ b/Windows/main.cpp
@@ -720,16 +720,16 @@ int WINAPI WinMain(HINSTANCE _hInstance, HINSTANCE hPrevInstance, LPSTR szCmdLin
 		{
 		case WINDOW_MAINWINDOW:
 			wnd = hwndMain;
-			accel = hAccelTable;
+			accel = g_Config.bSystemControls ? hAccelTable : NULL;
 			break;
 		case WINDOW_CPUDEBUGGER:
-			wnd = disasmWindow ? disasmWindow->GetDlgHandle() : 0;
-			accel = hDebugAccelTable;
+			wnd = disasmWindow ? disasmWindow->GetDlgHandle() : NULL;
+			accel = g_Config.bSystemControls ? hDebugAccelTable : NULL;
 			break;
 		case WINDOW_GEDEBUGGER:
 		default:
-			wnd = 0;
-			accel = 0;
+			wnd = NULL;
+			accel = NULL;
 			break;
 		}