diff --git a/Common/System/OSD.h b/Common/System/OSD.h
index 5c58e69a37..35ce345651 100644
--- a/Common/System/OSD.h
+++ b/Common/System/OSD.h
@@ -14,6 +14,7 @@ enum class OSDType {
 	MESSAGE_ERROR,
 	MESSAGE_ERROR_DUMP,  // displays lots of text (after the first line), small size
 	MESSAGE_FILE_LINK,
+	MESSAGE_CENTERED_WARNING,
 
 	ACHIEVEMENT_UNLOCKED,
 
diff --git a/Core/ConfigValues.h b/Core/ConfigValues.h
index 4db23f461d..3e762d632c 100644
--- a/Core/ConfigValues.h
+++ b/Core/ConfigValues.h
@@ -151,6 +151,7 @@ enum class ScreenEdgePosition {
 	TOP_RIGHT = 5,
 	CENTER_LEFT = 6,
 	CENTER_RIGHT = 7,
+	CENTER = 8,  // Used for REALLY important messages! Not RetroAchievements notifications.
 	VALUE_COUNT,
 };
 
diff --git a/UI/EmuScreen.cpp b/UI/EmuScreen.cpp
index 4611856340..ee9c31f2eb 100644
--- a/UI/EmuScreen.cpp
+++ b/UI/EmuScreen.cpp
@@ -273,6 +273,11 @@ void EmuScreen::bootGame(const Path &filename) {
 	if (!info || info->pending)
 		return;
 
+	auto sc = GetI18NCategory(I18NCat::SCREEN);
+	if (info->fileType == IdentifiedFileType::PSP_DISC_DIRECTORY) {
+		g_OSD.Show(OSDType::MESSAGE_CENTERED_WARNING, sc->T("Warning: Extracted ISOs often don't work. Play the ISO file directly."), 7.0f);
+	}
+
 	extraAssertInfoStr_ = info->id + " " + info->GetTitle();
 	SetExtraAssertInfo(extraAssertInfoStr_.c_str());
 
@@ -283,7 +288,6 @@ void EmuScreen::bootGame(const Path &filename) {
 
 		g_Discord.SetPresenceGame(info->GetTitle().c_str());
 	} else {
-		auto sc = GetI18NCategory(I18NCat::SCREEN);
 		g_Discord.SetPresenceGame(sc->T("Untitled PSP game"));
 	}
 
diff --git a/UI/OnScreenDisplay.cpp b/UI/OnScreenDisplay.cpp
index df6915d04b..5ce6af5a4b 100644
--- a/UI/OnScreenDisplay.cpp
+++ b/UI/OnScreenDisplay.cpp
@@ -53,7 +53,9 @@ static NoticeLevel GetNoticeLevel(OSDType type) {
 	case OSDType::MESSAGE_INFO: return NoticeLevel::INFO;
 	case OSDType::MESSAGE_ERROR:
 	case OSDType::MESSAGE_ERROR_DUMP: return NoticeLevel::ERROR;
-	case OSDType::MESSAGE_WARNING: return NoticeLevel::WARN;
+	case OSDType::MESSAGE_WARNING:
+	case OSDType::MESSAGE_CENTERED_WARNING:
+		return NoticeLevel::WARN;
 	case OSDType::MESSAGE_SUCCESS: return NoticeLevel::SUCCESS;
 	default: return NoticeLevel::SUCCESS;
 	}
@@ -290,6 +292,7 @@ void OnScreenMessagesView::Draw(UIContext &dc) {
 	typeEdges[(size_t)OSDType::LEADERBOARD_STARTED_FAILED] = (ScreenEdgePosition)g_Config.iAchievementsLeaderboardStartedOrFailedPos;
 	typeEdges[(size_t)OSDType::LEADERBOARD_SUBMITTED] = (ScreenEdgePosition)g_Config.iAchievementsLeaderboardSubmittedPos;
 	typeEdges[(size_t)OSDType::ACHIEVEMENT_UNLOCKED] = (ScreenEdgePosition)g_Config.iAchievementsUnlockedPos;
+	typeEdges[(size_t)OSDType::MESSAGE_CENTERED_WARNING] = ScreenEdgePosition::CENTER;
 
 	dc.SetFontScale(1.0f, 1.0f);
 
@@ -390,6 +393,7 @@ void OnScreenMessagesView::Draw(UIContext &dc) {
 		case ScreenEdgePosition::BOTTOM_RIGHT: horizAdj = 1; vertAdj = 1; break;
 		case ScreenEdgePosition::TOP_CENTER:  vertAdj = -1; break;
 		case ScreenEdgePosition::BOTTOM_CENTER: vertAdj = 1; break;
+		case ScreenEdgePosition::CENTER: break;
 		default: break;
 		}