diff --git a/plugins/spu2-x/src/Mixer.cpp b/plugins/spu2-x/src/Mixer.cpp
index 62874094e1..62d9dbed31 100644
--- a/plugins/spu2-x/src/Mixer.cpp
+++ b/plugins/spu2-x/src/Mixer.cpp
@@ -612,8 +612,9 @@ static __forceinline StereoOut32 MixVoice( uint coreidx, uint voiceidx )
 	else
 	{
 		// Continue processing voice, even if it's "off". Or else we miss interrupts! (Fatal Frame engine died because of this.)
-		if ((vc.LoopFlags & 3) != 3 || vc.LoopStartA != (vc.NextA & ~7)		// not in a tight loop
-			|| thiscore.IRQEnable && (thiscore.IRQA & ~7) == vc.LoopStartA	// or should be interrupting regularly
+		if ((*GetMemPtr(vc.NextA & 0xFFFF8) >> 8 & 3) != 3 || vc.LoopStartA != (vc.NextA & ~7)		// not in a tight loop
+			|| Cores[0].IRQEnable && (Cores[0].IRQA & ~7) == vc.LoopStartA	// or should be interrupting regularly
+			|| Cores[1].IRQEnable && (Cores[1].IRQA & ~7) == vc.LoopStartA
 			|| !(thiscore.Regs.ENDX & 1 << voiceidx))						// or isn't currently flagged as having passed the endpoint
 		{
 			UpdatePitch(coreidx, voiceidx);