diff --git a/cmake/SearchForStuff.cmake b/cmake/SearchForStuff.cmake
index 17e9c5e6d0..c520ecc42e 100644
--- a/cmake/SearchForStuff.cmake
+++ b/cmake/SearchForStuff.cmake
@@ -163,7 +163,9 @@ else()
 		find_package(X11 REQUIRED)
 		make_imported_target_if_missing(X11::X11 X11)
 	endif()
-	if(UNIX)
+	if(APPLE)
+		check_lib(GIO gio-2.0 gio/gio.h)
+	elseif(UNIX)
 		# Most plugins (if not all) and PCSX2 core need gtk2, so set the required flags
 		if (GTK2_API)
 			find_package(GTK2 REQUIRED gtk)
diff --git a/pcsx2/CMakeLists.txt b/pcsx2/CMakeLists.txt
index cea70b91ba..f6c14a4b85 100644
--- a/pcsx2/CMakeLists.txt
+++ b/pcsx2/CMakeLists.txt
@@ -1468,6 +1468,12 @@ if(WIN32)
 		opengl32.lib
 		comsuppw.lib
 	)
+elseif(APPLE)
+	target_link_libraries(PCSX2_FLAGS INTERFACE
+		PkgConfig::GIO
+		PCAP::PCAP
+		LibXml2::LibXml2
+	)
 else()
 	target_link_libraries(PCSX2_FLAGS INTERFACE
 		GTK::gtk